WebFosfomycin is a broad-spectrum antibiotic discovered in Spain in 1969. It has bactericidal activity against a wide range of bacteria, including gram-negative micro-organisms and some gram-positive bacteria, such as staphylococci. Initially fosfomycin was administered parenterally and only to patients with severe infections. WebNov 28, 2024 · The aim of this study is to establish the bacterial epidemiology of chronic osteoarticular infections in adults, to study the susceptibility of the isolated strains to …
[Fosfomycin] - PubMed
WebApr 1, 2008 · In an era in which there is a shortage of new antibiotics, fosfomycin might be considered to be an alternative treatment agent for infections caused by gram-positive and gram-negative bacteria, in addition to its traditional use in treating uncomplicated urinary tract and gastrointestinal infections. WebNov 28, 2024 · High efficiency of bone antibiotics are also more involved in bacterial resistance selection (rifampicin, fosfomycin, fluoroquinolones, clindamycin, fusidic acid). Deep localization of the OA infection significantly limits the spread of antibiotics. shaq charity work
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WebFosfomycin is an natural antibiotic with an epoxide structure and low molecular weight which acts in the first stage of peptidoglycan synthesis of the bacterial wall. ... including urinary, respiratory, intraabdominal, obstetric-gynecologic, central nervous system and osteoarticular infections, with satisfactory overall results in 80% of cases ... WebOct 31, 2024 · Fosfomycin disodium is currently available in only a few European countries—namely, Spain, France, Germany, the United Kingdom, the Netherlands, Austria, and Greece—where it is approved for the treatment of soft-tissue infection and sepsis. A Fosfomycin disodium adult dose of 12–24 g daily is commonly administered in 2–4 … WebBackground: Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due to MDR pathogens.Objective: The aims were to conduct population pharmacokinetics of fosfomycin in a cohort of OI patients receiving 16g/daily by intermittent (II) or continuous infusion (CI), and to carry out Monte Carlo simulations for … pooka theme song