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Emp2 antibody

WebEpithelial membrane protein-2 (EMP2) is a member of the four transmembrane superfamily (TM4SF) and is thought to mediate trafficking of diverse proteins such as alpha6beta1 integrin and MHC class I to lipid raft microdomains. EMP2 has also recently been recognized as a putative tumor suppressor gene in certain model systems. Sequence WebJan 2, 2024 · As the antibody-antigen complex rapidly internalizes, we have created an anti-EMP2 drug conjugate to improve on the efficacy of the naked antibody. Our second generation antibody includes the toxin monomethyl auristatin (MMAE), a potent microtubule-disrupting toxin, conjugated to the fully human anti-EMP2 IgG1 through both …

Anti-EMP2 Antibodies Invitrogen - Thermo Fisher Scientific

WebTo test the hypothesis that EMP2 may be a suitable target for therapy, we constructed a fully human immunoglobulin G1 (IgG1) antibody specific for a conserved domain of human … WebJun 12, 2024 · To determine if antibody targeting could produce a similar effect, HEC1A/EMP2 or HEC1A/VC cells were incubated with control IgG1 or the anti-EMP2 IgG1 overnight in a hypoxic chamber. next day delivery brochures https://fourde-mattress.com

(PDF) Epithelial Membrane Protein-2 (EMP2) Antibody

WebEMP2 Antibodies. We offer EMP2 Antibodies for use in common research applications: Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot. Each EMP2 … WebOct 10, 2024 · EMP2 is not only a marker of human breast cancer stem cells but also a predictor of adverse clinical results. To evaluate whether EMP2 is a better target for distinguishing breast cancer cells, some studies on breast cancer cell lines used an anti-EMP2 monoclonal antibody to capture MCF-7 and MDA-MB231 breast cancer cells. WebView Rabbit Polyclonal anti-EMP2 Antibody (NBP3-03954). Validated Applications: WB. Validated Species: Human. Sample size available. next day delivery before christmas

EMP2 Antibodies - Novus Biologicals

Category:Epithelial membrane protein 2: Molecular interactions and …

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Emp2 antibody

Anti-EMP2 antibody (ab223718) Abcam

WebUseful information about the protein provided by UniProt. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role i n regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the ... WebThis antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies. All characterization data for ENSG00000213853 on the Human …

Emp2 antibody

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WebEMP2 Antibody (NBP3-17361): Novus Biologicals View Rabbit Polyclonal anti-EMP2 Antibody (NBP3-17361). Validated Applications: IHC, IHC-P. Validated Species: Human. Skip to main content Support: 1-888-506-6887 Items in Cart (0) [X] Quick Order Account COVID-19 Research Tools Antibodies Primary Antibodies Conjugated Antibodies WebEMP2 (XMP) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More …

WebGene name: Emp2 (Xmp) ; Protein name: Epithelial membrane protein 2 (EMP-2) ; Alternative: Protein XMP ; Organism: Mouse (Mus musculus). General Annotation Sub …

http://www.biodragon.cn/plus/pdf.php?aid=117562 WebMay 15, 2012 · When the EMP2 levels in response to treatment with the anti-EMP2 antibody fragment was monitored, the EMP2 levels on the HEC1A/EMP2 cell surface were notably reduced within 24 h relative to the negative control cells treated with the A10 isotype control diabody (Fig. 3b). These results suggested that binding of anti-EMP2 antibody …

WebNov 7, 2024 · ONCR-201 is a fully human recombinant monoclonal antibody developed to target and inhibit the function of epithelial membrane protein 2 (EMP2). EMP2 is a cancer promoting protein, highly expressed in epithelial malignancies and associated with tumorigenesis, with triple negative breast cancer highly prominent on that list.

WebApr 6, 2014 · Importantly, no change in cellular viability was measured in EMP2-negative HS578t cells even at high concentrations of the antibody. As anti-EMP2 IgG1 recognized murine EMP2, we determined if the antibody could elicit a similar response in the 4T1 mouse mammary tumor line. 4T1 cells were susceptible to anti-EMP2 IgG1 with an IC 50 … millcreek coffeeWebInvitrogen Anti-EMP2 Polyclonal, Catalog # PA5-42011. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts with Human samples. Supplied as 100 µL purified … millcreek commons ice rinkWebAs a proof of principle to determine whether EMP2 could serve as a target for therapy, cells were treated using specific anti-EMP2 antibody reagents. These reagents were effective in killing GBM cells in vitro and in reducing tumor load in subcutaneous mouse models. mill creek community association trailWebEpithelial membrane protein 2 (EMP2) is a cell surface protein that has recently emerged as an object of neuro-oncological interest due to its potential to be utilized as a biomarker … mill creek coffee companyWebAnti-EMP2 antibody produced in rabbit (Anti-EMP-2 ); Prestige Antibodies Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution; Suitable … next day delivery chocolates ukWebJan 15, 2024 · Results: Anti-EMP2 antibody, compared to control antibody or vehicle, significantly reduced neovascularization as measured by clinical score and central cornea thickness, as well as by histologic ... millcreek community hospital behavioral unitWebSpecificity: This EMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the C-terminal region of human EMP2. Dilution: WB,1:1000;IHC-P,1:10~50; Purification: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This next day delivery card uk