Klf2 cxcr6
WebTissue-resident memory T cells or T RM cells represent a subset of a long-lived memory T cells that occupies epithelial and mucosal tissues (skin, mucosa, lung, brain, pancreas, gastrointestinal tract) without recirculating. T RM cells are transcriptionally, phenotypically and functionally distinct from central memory (T CM) and effector memory (T EM) T cells … WebOct 1, 2024 · We, therefore, identified CXCR6 + ST2 + memory Th2 cells as a critical …
Klf2 cxcr6
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WebChemokine receptors Cxcr3, Cxcr6, Ccr5, and Ccr9 were up-regulated (Fig. 5D), similar to CD8 TRM transcriptional changes in the liver and characterization of hepatic CD4 TRM by flow cytometry (36, 38). The cytokine receptors up-regulated in CD4 TRM included Il7r, Il2ra, and, to a lesser extent, Il12rb1 and Il21r (Fig. 5D). WebOct 13, 2024 · Krüppel-like factor 2 (KLF2), a transcription factor of the krüppel-like family, is a key regulator of activation, differentiation, and migration processes in various cell types. In this review, we focus on the functional relevance of …
WebNov 15, 2024 · At the transcriptomic level, these clusters were characterized by the common expression of ILC1-related genes, such as Cxcr6, Tmem176a, Tmem176b, Cd160, and Tnfsf10 (encoding TRAIL), whereas several other genes, such as Nr4a1, Ikzf2, Litaf, and Icam1, displayed tissue-restricted expression patterns ( Figure 1 D). WebJun 21, 2024 · The CXCR6-deficiency mice could increase the host control of tuberculosis …
WebMar 1, 2024 · KLF2, a member of the Kruppel-like factor family, has diverse roles in the immune system, and in particular plays a critical role in controlling migration of T (and B) cells via its control of expression of key homing receptors which determine selective trafficking capabilities. Other functions of KLF2 remain mostly undefined. WebJan 4, 2024 · LSEC capillarization is associated with fibrotic HCC progression and poor survival in both murine HCC model and HCC patients. We further found simvastatin restores the quiescence of activated hepatic stellate cells (aHSCs) via stimulation of KLF2-NO signaling in LSECs, and up-regulates the expression of CXCL16 in LSECs.
WebMar 21, 2024 · KLF2 (KLF Transcription Factor 2) is a Protein Coding gene. Diseases …
WebNov 25, 2010 · KLF4 and KLF2 are phylogenetically related KLF family members. 11–13 KLF2 is also expressed in monocytes; however, accumulating studies have revealed an anti-inflammatory role for KLF2 in these cells. 22,71 Das et al demonstrated that KLF2 expression is reduced on LPS stimulation in the THP-1 monocyte-like cell line. 71 … can allergies make it hard to swallow foodWebAug 17, 2024 · The increased expression of CXCR3 might provide a mechanistic understanding of the role T RM play in type 1 responses in certain tissues such as the lungs, as CXCL9, CXCL10, and CXCL11 are ligands for CXCR3 and are commonly released at local inflammatory sites during type 1 responses ( 31 ). fisher price farmyardWebApr 9, 2024 · KLF2(+) stemness maintains human mesenchymal stem cells in bone regeneration. Kruppel-like factor 2 disturb non-small cell lung cancer energy metabolism by inhibited glutamine consumption. KLF2 regulates neutrophil migration by modulating CXCR1 and CXCR2 in asthma. KLF2 inhibits TGF-beta-mediated cancer cell motility in … can allergies make it hard to swallowWebOct 12, 2024 · CXCR6 is a receptor for the chemokine CXCL16, which exists as a membrane or soluble form. CXCR6 is a marker for resident memory T (T RM) cells that plays a role in immunosurveillance through their interaction with epithelial cells.The interaction of CXCR6 with CXCL16 expressed at the membrane of certain subpopulations of intratumor … fisher price farm setWebProceedings of the National Academy of Sciences of the United States of ... can allergies make vision blurryWebAug 20, 2024 · TEM and LLE cells both had high activity of regulons related to T-cell … fisher price farm to kitchenWebIn the mouse model of a two-event TRALI induced by intraperitoneal injections with lipopolysaccharide and anti-H-2Kd mAb, we determined expression patterns of miR-144, Krüppel-like factor 2 (KLF2), chemokine (C-X-C motif) receptor 1 (CXCR1) and nuclear factor kappa-B (NF-kappaB) p65. fisher price farm toy