Tsc1 antibody
WebAug 24, 2012 · The endogenous interaction of TBC1D7 with the TSC1-TSC2 complex was confirmed in reciprocal immunoprecipitations with a panel of six unique antibodies to TSC1 or TSC2, along with an antibody raised against TBC1D7 (Figure 1 B), the specificity of which was confirmed through siRNA-mediated knockdown of TBC1D7 (Figure S1 E).TBC1D7 …
Tsc1 antibody
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WebJul 23, 2024 · The localization of Tsc1 in human skin (C) and colon (D) specimens was analyzed the same way using another primary Tsc1 antibody. The subcellular localization … WebTSC1 antibody; see all. Images. Western blot - Anti-TSC-1 antibody (ab200728) All lanes : Anti-TSC-1 antibody (ab200728) Lane 1 : HEK293T whole cell lysate Lane 2 : sp2/0 whole cell lysate Lane 3 : H9C5 whole cell lysate Predicted band …
WebMedium consistency between antibody staining and RNA expression data. Medium consistency between antibody staining and RNA expression data. WESTERN BLOT i … WebHuman/Mouse/Rat TSC1 Antibody Summary. Detects human, mouse, and rat TSC1 in direct ELISAs and Western blots. Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
WebMonoclonal Antibody for studying Hamartin/TSC1. Cited in 10 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Hamartin/TSC1 (1B2) Mouse Monoclonal Antibody (CST #4963) is … WebAntibody-bead conjugates were prepared by adding 2 µg of TSC1 monoclonal antibody ( Product # 37-0400) with 30 µL of protein G-Sepharose beads and rocked overnight at 4°C. …
WebThis is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth. A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown. Application Note. Anti-TSC1 Antibody has been tested for use in ELISA and Western ...
Weba 15 amino acid peptide from the middle region of human TSC1. TSC1 antibody will recognize both isoforms of TSC1. Packaging. 100 μg. Linkage. The action of this antibody can be blocked using blocking peptide SBP3505. Physical form. Solution in phosphate buffered saline containing 0.02% sodium azide. thrall robes skyrim seWebMar 21, 2024 · In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, 28215400, 35772404).Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity … thrall rdWebTSC1 antibody; see all. Images. Western blot - Anti-TSC-1 antibody (ab217328) All lanes : Anti-TSC-1 antibody (ab217328) at 0.5 µg/ml Lane 1 : Colo320 whole cell lysate Lane 2 : … underwrap sports tapeWebFeb 5, 2024 · How activated B cells build biosynthetic pathways and organelle structures necessary for subsequent robust antibody secretion is still unclear. The dominant model holds that nascent plasma cells adapt to increased antibody synthesis by activating the unfolded protein response (UPR) under the control of the transcription factor Xbp1. under wraps mclaren vale shiraz 2017WebApr 7, 2008 · Sensitivity and specificity of a rabbit monoclonal anti-TSC1 antibody was confirmed by staining of paraffin-embedded pellets of TSC1-null HCV29 cells and HCV29 in which wild-type TSC1 had been re-expressed (Fig. 7 A and D). Normal ureter showed strong cytoplasmic TSC1 expression in the urothelium (Fig. 7 E). thrall real estateWebHerein, we show that a recombinant fusion protein of a humanized antibody to CD40 fused to HPV16.E6/7 (αCD40-HPV16.E6/7) can evoke HPV16.E6/7-specific CD8+ and CD4+ T-cell responses in head-and ... under wraps movie trailerWebFeb 4, 2024 · Tuberous sclerosis complex subunit 1 (TSC1) and 2 (TSC2) are frequently mutated in non–small cell lung cancer (NSCLC), however, their effects on antitumor immunity remained unexplored.A CRISPR screening in murine Kras G12D /Trp53 −/− (KP) model identified Tsc1 and Tsc2 as potent regulators of programmed cell death ligand 1 … under wraps parents guide